http://debbybruck.hubpages.com/hub/Fosamax-Drug-Effects-Causing-Severe-Femur-Fractures-Brittle-Bones
Ever since drugs to combat osteoporosis started being prescribed, I began to wonder whether they would not be interfering with the normal bone health regulation cycle. Healthy bone is, at all times, being built and remodelled; old bone cells being killed within the body. Osteoblasts are the bone building cells and osteoclasts are the cells that take away old cells, unhealthy cells and hence help to remodel bone tissue. As age progresses, the bone building activity reduces, hence the breakdown of bone cells takes on a predominant role.
Drugs for osteoporosis inhibit the activity of osteoclasts. Common sense then tells me that under the influence of these drugs, healthy bone remodelling will not occur as it should. Old bone cells, unhealthy bone cells will not get destroyed as they should. Could this even lead to an increase in bone cancers? If there is a major reduction in osteoclastic activity, bone might then get too dense and rigid, lacking the amount of elasticity that it needs; this can then make the bones hard and brittle, thus increasing the risk of fractures after even slight trauma.
Studies are now showing that the osteoporosis drugs ARE in fact, leading to more brittle bones and more fractures. The excessive calcium deposits are leading to eye problems, heart ailments and embolic stroke.
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http://debbybruck.hubpages.com/hub/Fosamax-Drug-Effects-Causing-Severe-Femur-Fractures-Brittle-Bones